PENGARUH PEMBERIAN GEL BINAHONG TERHADAP PENYEMBUHAN LUKA SAYAT

DOI: https://doi.org/10.30989/mik.v9i3.699

Abstract

Background: Effective wound healing will reduce the costs incurred for treatment. Wound assessment, action and selection of treatment are carried out based on conditions and problems. Today's society prefers to do treatment by utilizing natural resources only on incision wounds given binahong leaves.

Objective: Produces a binahong gel composition that heals cuts and minimizes infection in the incision.

Methods: This research is included in inferential quantitative with parametric data. The mean difference test was then performed, followed by a paired t-test.

Results: Administration of Na CMC On day 10 the mean wound closed was 18.83 cm with a standard deviation of 1.15. The administration of 1% binahong gel obtained an average wound healing area of 19.54 cm with a standard deviation of 0.18. The administration of 5% binahomg gel on the 6th day only showed wound healing with a T test value of 0.004 but on day 8 there was no additional wound closure with an average wound healing area of 6.36. The administration of 7.5% gel was known until the 10th day indicating that there was no wound healing. Giving Povidone iodine is known to be on the 8th day showing wound healing with an average wound healing of 6.65 cm.

Conclusion: The 1% binahong gel was more effective in accelerating the healing of cuts in rats compared to the 5% and 7.5% binahong gel.

Author Biographies

Deby Zulkarnain Rahadian Syah, Universitas Jenderal Achmad Yani Yogyakarta

Nursing Manajemen

Nofran Putra Pratama, Universitas Jenderal Achmad Yani Yogyakarta

Prodi Farmasi (S1)

References

1. Wintoko R, Dwi A, Yadika N, Terkini M, Luka P. Manajemen Terkini Perawatan Luka. J Kedokt Univ Lampung [Internet]. 2020 Oct 2 [cited 2022 Jan 14];4(2):183–9. Available from: https://juke.kedokteran.unila.ac.id/index.php/JK/article/view/2893
2. Rida WN, Taharuddin T. Efektifitas Pemberian Daun Binahong (Anredera Cordifolia (Ten.) Steenis) Terhadap Penyembuhan Luka Sayatan Pada Tikus: Literature Review. Borneo Student Res [Internet]. 2021 Apr 27 [cited 2022 Jan 14];2(2):1024–31. Available from: https://journals.umkt.ac.id/index.php/bsr/article/view/1605
3. Toban CR, Kesumaningsih RF, Widiyono. Daun Binahong untuk Penyembuhan Luka. Media Ilmu Kesehat. 2012;1(1):19–24.
4. Audrey B, Snynder S, Kosier B, Erb G. Buku Ajar Praktik Keperawatan Klinis. 5th ed. Jakarta: EGC; 2009.
5. Mansjoer A. Kapita Selekta Kedokteran. 3rd ed. Jakarta: Media Aesculapius FKUI;
6. Depkes RI, Materia Medika Indonesia. Indonesia; 1977.
7. Harborne JB. Fitokimia : Penuntun Cara Modern Menganalisis Tumbuhan. Bandung: ITB; 1987.
8. Ainurrochmah A, Ratnasari E, Lisdiana L. Efektivitas Ekstrak Daun Binahong (Anredera cordifolia) terhadap Penghambatan Pertumbuhan Bakteri Shigella flexneri dengan Metode Sumuran. Lenterabio [Internet]. 2013 [cited 2019 Sep 25];2(3):233–7. Available from: https://jurnalmahasiswa.unesa.ac.id/index.php/lenterabio/article/viewFile/4343/6744
9. Tolistiawaty I, Widjaja J, Pamela P, Octaviani. Gambaran Kesehatan Mencit (Mus Musculus). J Vektor Penyakit. 2014;8(1):27–32.
10. Hariningsih Y. Pengaruh Variasi Konsentrasi Na-CMC Terhadap Stabilitas Fisik Gel Ekstrak Pelepah Pisang Ambon (Musa paradisiaca L.). Para Pemikir. 2019;8(2):46–51.
11. Maulina L, Sugihartini N. Formulasi Gel Ekstrak Etanol Kulit Buah Manggis (Garcinia Mangostana L.) Dengan Variasi Gelling Agent Sebagai Sediaan Luka Bakar. Pharmaciana [Internet]. 2015 May 31 [cited 2019 Sep 19];5(1). Available from: http://journal.uad.ac.id/index.php/PHARMACIANA/article/view/2285
12. Ardiana T, Putri Kusuma AR, Dian Firdausy M. Efektivitas Pemberian Gel Binahong (Anredera Cordifolia) 5% Terhadap Jumlah Sel Fibroblast Pada Soket Pasca Pencabutan Gigi Marmut (Cavia Cobaya). Odonto Dent J. 2015;2(1):64–70.
13. Tomayahu R, Bialangi N, Salimi YK. IdentifikasiSenyawaAktifdanUjiToksisitasEkstrakDaunBinahong (AnrederacordifoliaTen. Steenis) denganMetodeBrine Shrimp Lethality Test(BSLT). Universitas Negeri Gorontalo; 2014.
14. Muiz A. Pengaruh Penggunaan Tepung Daun Binahong (Andredera Cordifolia)(Ten)(Stennis) Sebagaifeed Additive Terhadap Kualitas Karkasayam Pedaging. J Agrisains. 2016;17(1):54–61.
15. Kintoko K, Novitasari, P.R. Novitasari PR. Studi In Vivo Efektivitas Gel Ekstrak Etanol Daun Binahong (Anredera cordifolia (Tenore) Steen) Sebagai Penyembuh Luka Diabetes. Proceeding Mulawarman Pharm Conf [Internet]. 2016 Apr 26 [cited 2019 Sep 28];3:253–64. Available from: http://prosiding.farmasi.unmul.ac.id/index.php/mpc/article/view/117
16. Rohma SC, Holidah D, Ulfa EU. Pengaruh Gel Binahong (Anredera cordifolia (Ten.) Steenis) terhadap Penyembuhan Luka Tikus Diabetes yang Diinduksi Aloksan. J Pustaka Kesehat. 2015;3(3).
17. Khoswanto C, Soehardjo I. The effect of Binahong Gel (Anredera cordifolia (Ten.) Steenis) in accelerating the escalation expression of HIF-1α and FGF-2. J Int Dent Med Res [Internet]. 2018 [cited 2019 Sep 28];11(1). Available from: http://www.jidmr.com/journal/wp-content/uploads/2018/04/58D17_482_Christian_Khoswanto.pdf
18. Istyastono EP, Yuliani SH. Scarless wound healing gel with Binahong (Anredera cordifolia (Ten) Steenis) leaves extract and celecoxib as the active ingredients. In: AIP Conference Proceedings [Internet]. AIP Publishing LLC; 2016 [cited 2019 Sep 28]. p. 160001. Available from: http://aip.scitation.org/doi/abs/10.1063/1.4958594
19. Pebri IG, Rinidar R, Amiruddin A. Pengaruh Pemberian Ekstrak Daun Binahong (Anredera Cordifolia) Terhadap Proses Penyembuhan Luka Insisi (Vulnus Incisivum) Pada Mencit (Mus Musculus). J Ilm Mhs Vet [Internet]. 2017 Nov 2 [cited 2019 Sep 28];2(1):1–11. Available from: http://www.jim.unsyiah.ac.id/FKH/article/view/5655
20. Kintoko, Karimatulhajj H, Elfasyari TY, Ihsan EA, Putra TA. Effect of Diabetes Condition on Topical Treatment of Binahong Leaf Fraction in Wound Healing Process. Tradit Med J. 2017;22(2):103–10.
Published
2022-01-17
How to Cite
1.
Rahadian Syah DZ, Putra Pratama N. PENGARUH PEMBERIAN GEL BINAHONG TERHADAP PENYEMBUHAN LUKA SAYAT. Media ilmu kesehatan [Internet]. 2022Jan.17 [cited 2024Apr.19];9(3):259-68. Available from: https://ejournal.unjaya.ac.id/index.php/mik/article/view/699
Issue
Vol 9 No 3 (2020): Media Ilmu Kesehatan
Section
Articles

Articles received and published by the Media Ilmu Kesehatan are by the publication, the copyright of the article is fully transferred to the Media Ilmu Kesehatan. All operational forms such as printing, publication, and distribution of hard file journals are carried out by the Media Ilmu Kesehatan. Articles that have finished the review process and have been declared accepted by the journal manager or editor will be asked to fill out a statement of submission of copyright by the journal secretary to the main author or correspondent author. The statement of transfer of copyright is signed with a seal and sent via email to journalmik2018@gmail.com and contacted the admin of the journal to be followed up on archiving. Journal managers and editors have the right to edit the manuscript according to the provisions of the writing rules in the Media Ilmu Kesehatan.

Articles that have been declared accepted either online through the author's account on the OJS website https://ejournal.unjaya.ac.id/index.php/mik or a letter of receipt of the article (LOA), as well as those that have been published on OJS are not allowed to be published in other journals, or proceedings. The number of authors with more than one and as the main author or designated as the correspondent writer must have coordinated with members of the research team. The order of the authors submitted in the article as the author of one, two, three and so on cannot be changed when the article is published unless an error occurs in the technical operation of the journal.