Deteksi Varian Rhesus Dweak pada Populasi Rhesus Negatif di Provinsi DKI Jakarta

Authors

  • Endang Pratiwi Program Magister Ilmu Biomedik, Fakultas Kedokteran, Universitas Indonesia
  • Ni Ken Ritchie UDD PMI Provinsi DKI Jakarta
  • Heri Wibowo Departemen Parasitologi, Fakultas Kedokteran, Universitas Indonesia

DOI:

https://doi.org/10.30989/mik.v11i2.744

Keywords:

Detection, Rhesus, Variant

Abstract

Background: The Rhesus blood group system is determined by the presence or absence of the D-antigen, and has clinical importance because it can cause Haemolytic Transfusion Reaction (HTR) and Haemolytic Disease of the Newborn (HDN). There are several variants of the D-antigen which are weak, so it will be detected as Rhesus Negative.
Objective: The purpose of this study was to determine the prevalence of the Rhesus D weak blood group variant in DKI Jakarta Province, so that it could determine the identity status of the blood group correctly.
Methods: The samples used in this study were whole blood samples with a maximum storage time of three days in the blood refrigerator. The examination used in this study is the Indirect Antiglobulin Test (IAT).
Results: Rhesus Dweak variant was detected in 103 samples examined using the IAT examination method.
Conclusion: Determination of the Rhesus variant in individuals is necessary to prevent clinical impact on the patient. Further examination is needed to ensure the D-antigen of the Rhesus blood group

Author Biography

Ni Ken Ritchie, UDD PMI Provinsi DKI Jakarta

Program Magister Ilmu Biomedik, Fakultas Kedokteran, Universitas  Indonesia, Diploma 3 Teknisi Bank Darah Akademi Bakti Kemuliaan PMI

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Published

2023-03-04

How to Cite

1.
Endang Pratiwi, Ritchie NK, Wibowo H. Deteksi Varian Rhesus Dweak pada Populasi Rhesus Negatif di Provinsi DKI Jakarta. Media ilmu kesehatan [Internet]. 2023 Mar. 4 [cited 2024 Dec. 22];11(2). Available from: https://ejournal.unjaya.ac.id/index.php/mik/article/view/744