EVALUASI PENGGUNAAN TERAPI ANTIHIPERTENSI PADA PASIEN GAGAL GINJAL KRONIK DENGAN HEMODIALISIS

  • Nadia Husna Universitas Jenderal Achmad Yani Yogyakarta
  • Niken Larasati Universitas Jenderal Achmad Yani Yogyakarta
DOI: https://doi.org/10.30989/mik.v8i1.249

Abstract

Background: End Stage Renal Disease (ESRD) occurs when Glomerular Filtration Rate (GFR) falls below 15 ml/minute/1.73m2. This condition leads to Renal Replacement Therapy (RRT) intervention namely dialysis and kidney transplantation. The intervention inclines morbidity and hospitalization rate which means more physical and financial burden to patients as the consequences. One of the physical side effects that becomes a major cause of increasing cardiovasculer mortality is hypertension.

Objective: The purpose of this study was to analyze the rationale of antihypertensive therapy in haemodialysis patients.

Methods: A descriptive, purposive, non experimental study gathering medical records of 97 hemodialysis with antihypertensive therapy patients of PKU Muhammadiyah Gamping hospital who were admitted from June until August 2018 was held in this study.

Results: Majority of patients were female (63,92%), aged between 41-75 years (83,50%), and diagnosed with chronic kidney disease (CKD) (95,58%), received three combination of antihypertensive drugs (38,14%) using Calcium Channel Blocker namely amlodipin (20,86%). The analysis of antihypertensive therapy including accurate drugs, patients, and dosage were 83,51%, 100%, and 97,72% respectively.

Conclusion: The use of antihypertensive drugs in CKD patient in PKU Muhammadiyah Gamping was approprite

Keywords: Antihypertension, chronic kidney disease, evaluation, hemodialysis, hospital.

Author Biographies

Nadia Husna, Universitas Jenderal Achmad Yani Yogyakarta

Prodi Farmasi, Fakultas Kesehatan, Jl. Brawijaya Ambarketawang Gamping Sleman Yogyakarta

Niken Larasati, Universitas Jenderal Achmad Yani Yogyakarta

Prodi Farmasi, Jl. Brawijaya Ambarketawang Gamping Sleman Yogyakarta

References

1. Dipiro T, et al.Pharmacotherapy Handbook 9th Edition. 2015. Mc Graw Hill Education.
2. 8th Joint National Committee of Hypertension.JNC 8 Guidelines Algorithm. 2013.
3. Agarwal, et al.Prevalence, Treatment, And Control Of Hypertension In Chronic Hemodialysis Patients In United States. 2003. Am J Med.
4. National Kidney Foundation.K/DOQI Clinical Practice Guidelines for Cardiovascular Disease in Dialysis Patients. 2005.
5. Muchtar, dkk. Studi Penggunaan Obat Antihipertensi Pada Pasien Gagal Ginjal Kronik Yang Menjalani Perawatan Di Rsup Prof. Dr. R. D. Kandou Manado Periode Juli 2013 - Juni 2014. Jurnal Ilmiah Farmasi. Vol. 4 No. 3 Agustus 2015 ISSN 2302 – 2493.
6. Priyadi, dkk. Evaluasi Penggunaan Obat Antihipertensi Pada Pasien Gagal GinjalKronik Di Salah Satu Rumah Sakit Swasta Di Kota Bandung. Prosiding Rakernas dan Pertemuan Ilmiah Tahunan Ikatan Apoteker Indonesia. 2016. e-ISSN : 2541-0474.
7. Yoshihiro, Taniyama.Management Of Hypertension For Patients Undergoing Dialysis Therapy. 2016. Renal Replacement Therapy.
8. Gormer, Beth. 2007. terj. Diana Lyrawati, 2008.Farmakologi Hipertensi lyrawati.files.wordpress.com.
9. Lacy, dkk. Drug Information Handbook 19th Edition. American Pharmacist’s Asociation. Lexi-comp. 2010.
Published
2019-11-18
How to Cite
1.
Husna N, Larasati N. EVALUASI PENGGUNAAN TERAPI ANTIHIPERTENSI PADA PASIEN GAGAL GINJAL KRONIK DENGAN HEMODIALISIS. Media ilmu kesehatan [Internet]. 2019Nov.18 [cited 2024Nov.19];8(1):1-. Available from: https://ejournal.unjaya.ac.id/index.php/mik/article/view/249
Issue
Vol 8 No 1 (2019): Media Ilmu Kesehatan
Section
Articles

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