Trends Research Medication Adherence of Hypertensive Patients: Bibliometric Analysis
Keywords:
Bibliometric analysis, Health education, Hypertension, Medication adherence, Mobile healthAbstract
Background: Hypertension is a serious global health problem. Medication adherence is one of the important factors in its control. However, hypertension patients' adherence to medication is still a major obstacle. Many studies have addressed medication adherence in hypertensive patients. However, the mapping of scientific contributions related to the topic is still limited. Therefore, bibliometric analysis is needed to identify them.
Purpose: This study aims to analyze publication trends and contributions of authors, sources, institutions, and countries, as well as potential future research directions in hypertension treatment adherence.
Methods: This study used bibliometric analysis with the Scopus database. Articles published between 2014 and 2023 were analyzed using the keywords "hypertension", "high blood pressure", "medication adherence", and "medication compliance", combined with boolean operators. The initial documents identified were 4,558 articles. The search focused on article titles, abstracts, keywords, restricted to publications in English, and completed metadata. A total of 3,100 articles met the inclusion and exclusion criteria for analysis.
Results: Scientific publications on hypertension medication adherence increased steadily over the period 2014-2023, with 364 publications in 2020 as the peak. By number of publications, the most prolific author was Bosworth with 28 articles, while the journal Patient Preference and Adherence led with 88 articles. The United States was the most productive country with 6,320 publications. Cluster analysis identified five main clusters, with hypertension and medication compliance as dominant topics and mobile health, health education, and adherence monitoring as emerging topics.
Conclusion: The topic of hypertension medication adherence remains important to research, with great potential in the currently under-discussed areas of mobile health and health education. Future research could focus on innovative interventions in these areas to improve patient medication adherence.
References
ABOUT UAB - The University of Alabama at Birmingham | UAB (no date). Available at: https://www.uab.edu/home/about (Accessed: 25 May 2024).
Ahmadvand, A. et al. (2019) ‘Trends and Visibility of “Digital Health” as a Keyword in Articles by JMIR Publications in the New Millennium: Bibliographic-Bibliometric Analysis’, Journal of Medical Internet Research, 21(12), p. e10477. doi: 10.2196/10477.
Alawneh, I. S., Yasin, A. and Musmar, S. (2022) ‘The Prevalence of Uncontrolled Hypertension among Patients Taking Antihypertensive Medications and the Associated Risk Factors in North Palestine: A Cross-Sectional Study’, Advances in Medicine. Edited by C. Dietrich, 2022, pp. 1–7. doi: 10.1155/2022/5319756.
Algabbani, F. M. and Algabbani, A. M. (2020) ‘Treatment adherence among patients with hypertension: findings from a cross-sectional study’, Clinical Hypertension, 26(1), p. 18. doi: 10.1186/s40885-020-00151-1.
Ampofo, A. G., Khan, E. and Ibitoye, M. B. (2020) ‘Understanding the role of educational interventions on medication adherence in hypertension: A systematic review and meta-analysis’, Heart & Lung, 49(5), pp. 537–547. doi: 10.1016/j.hrtlng.2020.02.039.
Anderson, L. J. et al. (2020) ‘A systematic overview of systematic reviews evaluating medication adherence interventions’, American Journal of Health-System Pharmacy, 77(2), pp. 138–147. doi: 10.1093/ajhp/zxz284.
Badan Kebijakan Pembangunan Kesehatan (2024) Survei Kesehatan Indonesia (SKI) Dalam Angka: Data Akurat Kebijakan Tepat. Kemenkes RI. Available at: https://www.badankebijakan.kemkes.go.id/ski-2023-dalam-angka/.
Badan Penelitian dan Pengembangan (2014) Laporan Nasional Riskesdas 2013. Jakarta: Kemenkes RI.
Badan Penelitian dan Pengembangan (2019) Laporan Nasional Riskesdas 2018. Jakarta: Kemenkes RI. Available at: https://repository.badankebijakan.kemkes.go.id/id/eprint/3514/.
Burnier, M. and Damianaki, A. (2023) ‘Hypertension as Cardiovascular Risk Factor in Chronic Kidney Disease’, Circulation Research, 132(8), pp. 1050–1063. doi: 10.1161/CIRCRESAHA.122.321762.
Burnier, M., Polychronopoulou, E. and Wuerzner, G. (2020) ‘Hypertension and Drug Adherence in the Elderly’, Frontiers in Cardiovascular Medicine, 7, p. 49. doi: 10.3389/fcvm.2020.00049.
Campos, K. J. et al. (2023) ‘Factors associated with adherence to pharmacological treatment by hypertensive patients: Fatores associados à adesão ao tratamento farmacológico por pacientes hipertensos’, Concilium, 23(11), pp. 291–302. doi: 10.53660/CLM-1446-23G16A.
Chowdhury, M. Z. I. et al. (2020) ‘Hypertension prevalence and its trend in Bangladesh: evidence from a systematic review and meta-analysis’, Clinical Hypertension, 26(1), p. 10. doi: 10.1186/s40885-020-00143-1.
Denisova, A. R. et al. (2022) ‘The incidence of cardiovascular and cerebrovascular complications in patients with uncontrolled hypertension’, Terapevticheskii arkhiv, 94(1), pp. 94–99. doi: 10.26442/00403660.2022.01.201395.
Devos, P. and Menard, J. (2019) ‘Bibliometric analysis of research relating to hypertension reported over the period 1997–2016’, Journal of Hypertension, 37(11), pp. 2116–2122. doi: 10.1097/HJH.0000000000002143.
Devos, P. and Ménard, J. (2020) ‘Trends in Worldwide Research in Hypertension Over the Period 1999–2018: A Bibliometric Study’, Hypertension, 76(5), pp. 1649–1655. doi: 10.1161/HYPERTENSIONAHA.120.15711.
Dhungana, R. R., Pandey, A. R. and Shrestha, N. (2021) ‘Trends in the Prevalence, Awareness, Treatment, and Control of Hypertension in Nepal between 2000 and 2025: A Systematic Review and Meta-Analysis’, International Journal of Hypertension. Edited by S. Corrao, 2021, pp. 1–11. doi: 10.1155/2021/6610649.
Kageyama, I. et al. (2022) ‘A Bibliometric Analysis of Wearable Device Research Trends 2001–2022—A Study on the Reversal of Number of Publications and Research Trends in China and the USA’, International Journal of Environmental Research and Public Health, 19(24), p. 16427. doi: 10.3390/ijerph192416427.
Karim, H. A. Z. B. et al. (2023) ‘Therapeutic Compliance in Hypertensive Patients: a Cross Sectional Study’, Journal of Hypertension, 41(Suppl 3), p. e314. doi: 10.1097/01.hjh.0000942264. 17329.f5.
Kokol, P., Blažun Vošner, H. and Završnik, J. (2021) ‘Application of bibliometrics in medicine: a historical bibliometrics analysis’, Health Information & Libraries Journal, 38(2), pp. 125–138. doi: 10.1111/hir.12295.
Lou, Y. et al. (2023) ‘Trends in exercise for hypertension: a bibliometric analysis’, Frontiers in Cardiovascular Medicine, 10, p. 1260569. doi: 10.3389/fcvm.2023.1260569.
Methley, A. M. et al. (2014) ‘PICO, PICOS and SPIDER: a comparison study of specificity and sensitivity in three search tools for qualitative systematic reviews’, BMC Health Services Research, 14(1), p. 579. doi: 10.1186/s12913-014-0579-0.
Mohammadi Torkabad, S., Negahban Bonabi, T. and Heidari, S. (2020) ‘Effectiveness of smartphone-based medication reminder application on medication adherence of patients with essential hypertension: A clinical trial study’, Journal of Nursing and Midwifery Sciences, 7(4), p. 219. doi: 10.4103/JNMS.JNMS_16_20.
Page, M. J. et al. (2021) ‘The PRISMA 2020 statement: an updated guideline for reporting systematic reviews’, BMJ, p. n71. doi: 10.1136/bmj.n71.
Patient Preference and Adherence - Impact Factor, Quartile, Ranking (no date). Available at: https://wos-journal.info/journalid/18265 (Accessed: 25 May 2024).
PLoS One - Impact Factor, Quartile, Ranking (no date). Available at: https://wos-journal.info/journalid/14784 (Accessed: 25 May 2024).
Podzolkov, V. I. et al. (2023) ‘Compliance to treatment and its role in solving the problem of uncontrolled hypertension’, Cardiovascular Therapy and Prevention, 22(4), p. 3547. doi: 10.15829/1728-8800-2023-3547.
Poulter, N. R. et al. (2020) ‘Medication adherence in hypertension’, Journal of Hypertension, 38(4), pp. 579–587. doi: 10.1097/HJH.0000000000002294.
Press, D. (no date) Patient Preference and Adherence | Journal metrics - Dove Press Open Access Publisher. Available at: https://www.dovepress.com/journal-editor-patient-preference-and-adherence-eic20 (Accessed: 25 May 2024).
Svarstad, B. L., Brown, R. L. and Shireman, T. I. (2022) ‘A successful intervention to improve medication adherence in Black patients with hypertension: Mediation analysis of 28-site TEAM trial’, Journal of the American Pharmacists Association, 62(3), pp. 800-808.e3. doi: 10.1016/j.japh.2022.01.002.
Sweileh, W. M. et al. (2019) ‘Bibliometric analysis of global publications in medication adherence (1900–2017)’, International Journal of Pharmacy Practice, 27(2), pp. 112–120. doi: 10.1111/ijpp.12471.
Tajudeen, F. P. et al. (2022) ‘Mobile Technologies and Healthy Ageing: A Bibliometric Analysis on Publication Trends and Knowledge Structure of mHealth Research for Older Adults’, International Journal of Human–Computer Interaction, 38(2), pp. 118–130. doi: 10.1080/10447318.2021.1926115.
Thompson, D. F. and Walker, C. K. (2015) ‘A Descriptive and Historical Review of Bibliometrics with Applications to Medical Sciences’, Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 35(6), pp. 551–559. doi: 10.1002/phar.1586.
Tian, H. and Chen, J. (2022) ‘A bibliometric analysis on global eHealth’, DIGITAL HEALTH, 8, p. 205520762210913. doi: 10.1177/20552076221091352.
Vrijens, B. et al. (2017) ‘Current Situation of Medication Adherence in Hypertension’, Frontiers in Pharmacology, 8. doi: 10.3389/fphar.2017.00100.
Ye, L. and Zhang, X. (2019) ‘Visualizing the knowledge structure of medication‐adherence research: A bibliometric analysis (1997‐2016)’, The International Journal of Health Planning and Management, 34(4), pp. 1333–1353. doi: 10.1002/hpm.2852.
